Medicine that inhibit CYP2D6 action, for example paroxetine and quinidine, may possibly result in lowered clearance of oxycodone which could lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by thirteen%, and t½ elim.These strengths could result in overdose (e

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